Advances in Neurochemistry: Volume 3 by Neil Raymond Sims, Patrick Robert Carnegie (auth.), B. W. PDF

By Neil Raymond Sims, Patrick Robert Carnegie (auth.), B. W. Agranoff, M. H. Aprison (eds.)

ISBN-10: 1461582407

ISBN-13: 9781461582403

ISBN-10: 1461582423

ISBN-13: 9781461582427

The unique premise of the Editors in starting up this sequence was once that there existed a readership ofneurochemists with substantial biochemical again­ flooring who may utilize a chain devoted to either new boost­ ments and really good experiences in neurochemistry. Having chosen our authors, we've got provided them nearly entire freedom to mirror and speculate in a box during which they've got accomplished prominence. The reaction to the 1st volumes has been worthwhile. the current one keeps during this culture. whereas we've not tried to post really good volumes, the current quantity includes a bit similar chapters (Chapters four and five, at the position of amino acid neurotransmitters). the 1st 3 chapters research 3 different methods, every one of present curiosity, in neurochemi­ cal ways to the molecular bases of neuronal and glial constitution. B. W. Agranoff M. H. Aprison vii CONTENTS bankruptcy 1 2',3'-CYCUC NUCLEOTIDE 3'-PHOSPHODIESTERASE NEIL RAYMOND SIMS AND PATRICK ROBERT CARNEGIE 1. advent. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1 2. Assay of CNPase . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . three 2. 1. desire for Activation. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . three 2. 2. comparability of Assays . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . three three. organization of CNPase with Myelin . . . . . . . . . . . . . . . . . . . . . . . 7 three. 1. ancient. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 7 three. 2. Subcellular Fractionation. . . . . . . . . . . . . . . . . . . . . . . . . . . . eight three. three. improvement. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . eight three. four. Mutant Mice . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . nine three. five. Use as a Myelin Marker . . . . . . . . . . . . . . . . . . . . . . . . . . . . 10 three. 6. Myelin-Related Fractions and Peripheral Nerve Myelin. eleven four. CNPase in Nonmyelin Fractions. . . . . . . . . . . . . . . . . . . . . . . . . . thirteen five. Activation and Isolation. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . thirteen five. 1. advent. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . thirteen five. 2. Activation. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 14 five. three. Solubilization and Fractionation. . . . . . . . . . . . . . . . . . . . . . 15 6. houses. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 19 6. 1. Substrate Specificity. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

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Riekkinen, P. , and Rumsby, M. , 1972, Aminopeptidase and neutral proteinase activity associated with central nerve myelin preparations during purification, Brain Res. 41:512517. Riekkinen, P. , Rinne, U. , Arstila, A. , and Pelliniemi, T. , 1972, Studies on the pathogenesis of multiple sclerosis. 2' ,3'-Cyclic nucleotide 3'-phosphohydrolase as marker of demyelination and correlation of findings with lysosomal changes, J. Neurol. Sci. 15:113-120. Rumsby, M. , Getliffe, H. , and Riekkinen, P. , 1973, On the association of nonspecific esterase activity with central nerve myelin preparations, J.

Exp. Neurol. 34:465-477. Richards, F. , and Wyckoff, H. , 1971, Bovine pancreatic ribonuclease, in: The EnzYmes (P. D. ), Vol. IV, pp. 647-806, Academic Press, New York. Riekkinen, P. , 1970, Peptidase activity of purified myelin, Acta Neurol. Scand. 46:93-101. Riekkinen, P. , and Rumsby, M. , 1972, Aminopeptidase and neutral proteinase activity associated with central nerve myelin preparations during purification, Brain Res. 41:512517. Riekkinen, P. , Rinne, U. , Arstila, A. , and Pelliniemi, T.

Mitzen, E. , Barron, K. , Koeppen, A. , and Harris, H. , 1974, Enzyme activity of human central nervous system myelin, Brain Res. 68:123-131. , 1976, Phosphorylation of endogenous proteins in myelin of rat brain, J. Neurochem. 26:573-577. , 1974, In vitro and in vivo phosphorylation of myelin basic protein by exogenous and endogenous adenosine 3' ,5'-monophosphate-dependent protein kinases in brain, J. BioI. Chern. 249:2769-2777. , 1975, Phosphoprotein phosphatases for myelin basic protein in myelin and cytosol fractions of brain, Biochim.

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Advances in Neurochemistry: Volume 3 by Neil Raymond Sims, Patrick Robert Carnegie (auth.), B. W. Agranoff, M. H. Aprison (eds.)


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